RGUHS Pharmacology
Practical Experiments
Select a module to open its full reference — bullet summaries, protocols, solved problems, and formula tables.
CMA, CEA, CUA, CBA and COI methods — ICER, QALY, DALY, WTP thresholds, sensitivity analysis, critical appraisal checklist, and India-specific context including HTAIn.
One-compartment IV bolus model — elimination kinetics, volume of distribution, clearance, AUC, infusion equations, oral absorption, and TDM applications.
Principles, types, and methods of bioassay — matching, bracketing, graphical interpolation, three-point and four-point assays with Latin square design.
Preclinical toxicity — acute, subacute, chronic, and special studies. LD50 calculation (Karber's method), mutagenicity, carcinogenicity, reproductive and local toxicity, GLP, and dose terms.
ADR monitoring and assessment — WHO-UMC causality scale, Naranjo algorithm, Hartwig-Siegel severity, Schumock-Thornton preventability, PVPI, signal detection methods, pharmacogenomics, and 5 case scenarios.
Computer-assisted learning on pupillary pharmacology — iris anatomy, miotic and mydriatic drug classification, rabbit eye experiment, volunteer experiments, glaucoma management, and 9 individual drug profiles.
Behavioural model for anxiety assessment in rodents — anxiolytic and anxiogenic drug screening using open and closed arm exploration.
Measurement of pain threshold in experimental animals — hot plate, tail flick, and other analgesic screening methods.